Research interests

Prabhat’s research focuses on the development of new photochemical transformation, visible light mediated multicomponent reactions employing flow chemistry and transition metal catalysis. Additionally, his research ambitiously extends into the realm of heterogeneous catalysis, focusing on the activation of triple bonds and employing Metal-Organic Frameworks (MOFs) as innovative catalysts for generating carbenes and nitrenes.

Funding: Marie Skłodowska-Curie Actions

A New Light on Isocyanide Synthesis (HORIZON-MSCA-2021)

SusIsocyanide is an ambitious project that aims for the sustainable synthesis of isocyanides by combining biobased feedstock, visible light and flow chemistry. The aim is to accomplish an economically viable and ecofriendly large scale synthesis of this fundamental and highly versatile building block that has already found widespread appreciation in academia, but suffers from underutilization in the pharma-, fine-chemicals and materials industry.

List of Publications (full publication list on Google Scholar)

1. Wu, M.; Saya, J. M.; Han, P.; Walia, R.; Pradhan, B.; Honing, M.; Ranjan, P.:* Orru, R. V.A.* Visible light-driven dearomatization of tryptamine-derived isocyanides through aggregation-based charge transfer. Chem. Sci., 2024, 15, 6867-6873.
2. Ranjan, P.; Pillitteri, S.; Coppola, G.; Oliva, M.; Van der Eycken, E.V.; Sharma, U. K.* Unlocking the accessibility of alkyl radicals from boronic acids through hydrogen-bond assisted organophotoredox activation. ACS Catalysis 2021, 11, 10862.
3. Ranjan, P.; Oliva, M.; Pillitteri, S.; Coppola, G.; Van der Eycken, E.V.; Sharma, U.K.* Photoredox-catalyzed multicomponent Petasis reaction in batch and continuous flow with alkyl boronic acid. iscience 2021, 24, 103134.
4. Ranjan, P.; Manno, R.; Sebastian, V.*; Mallada, R.; Irusta, S.; Sharma, U. K.; Van der Eycken, E. V.*; Santamaria, J. Continuous Microwave-Assisted Synthesis of Silver Nanoclusters Confined in Mesoporous SBA-15: Application in Alkyne Cyclizations. Mater. 2020, 32, 2874.
5. Ranjan, P.; Ojeda, G. M.; Sharma, U. K.*; Van der Eycken, E. V.* Metal-Free Dearomatization: Direct Access to Spiroindol(en)ines in Batch and Continuous-Flow. A Eur. J. 2019, 25, 244